解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::A new thin-target method (patent pending) is described for portal imaging with low-energy (tens of keV) photons from a medical linear accelerator operating in a special mode. Low-energy photons are usually produced in the accelerator target, but are absorbed by the target and flattening filter, both made of medium- or...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/8/016
更新日期:1998-08-01 00:00:00
abstract::The dose-response of LiF:Mg,Ti (TLD-100) exposed to 15 and 35 kVp (8.0 +/- 0.1 and 8.1 +/- 0.1 keV effective energy respectively) x-rays and 60Co gamma-rays has been measured in the dose interval from (1.2-5.4) x 10(3) Gy for x-rays, and from 0.14 to 850 Gy for gamma-rays. In both cases the total TL signal and glow cu...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/8/006
更新日期:1998-08-01 00:00:00
abstract::The design, construction and use of a large-scale field-cycled proton-electron double-resonance imaging (FC-PEDRI) imager is described. The imager is based on a whole-body sized, vertical field, 59 mT permanent magnet. Field cycling is accomplished by the field compensation method, and uses a secondary, resistive magn...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/7/008
更新日期:1998-07-01 00:00:00
abstract::Source anisotropy is a very important factor in the brachytherapy quality assurance of high-dose rate (HDR) 192Ir afterloading stepping sources. If anisotropy is not taken into account then doses received by a brachytherapy patient in certain directions can be in error by a clinically significant amount. Experimental ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/6/029
更新日期:1998-06-01 00:00:00
abstract::A leaf-setting algorithm is developed for generating arbitrary beam intensity profiles in discrete levels using dynamic multileaf collimators (DMLCs). The algorithm starts with the algebraic expression for the area under the beam profile. It is shown that the coefficients in this expression can be transformed into the...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/6/019
更新日期:1998-06-01 00:00:00
abstract::In radiotherapy with photon beams, the use of dynamic wedges, which are obtained by the movement of one of the jaws, offers an increasing flexibility relative to the traditional use of metal wedges. But it is a disadvantage for the measurement of absorbed dose distributions, because the absorbed dose at each measureme...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/6/009
更新日期:1998-06-01 00:00:00
abstract::Backscatter factors for orthovoltage x-ray beams are fitted with the expression BSF = 1 + ms/(s + n), where s is field size and m and n are adjustable parameters. The accuracy is better than 0.5%. Good results were also obtained for Cs-137 gamma rays at depth 0.12 cm and Co-60 gamma rays at depth 0.5 cm using the same...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/5/021
更新日期:1998-05-01 00:00:00
abstract::Temperature distributions resulting from hyperthermia treatments on isolated perfused bovine tongues were compared with simulations by a treatment planning system. The aim was to test whether the discrete vessel model used for the treatment planning is able to predict correct generic temperature distributions. Tongues...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/5/011
更新日期:1998-05-01 00:00:00
abstract::Several types of intravascular ultrasound (IVUS) catheters are connected to a motor at their proximal end, in order to let the catheter rotate around its length axis. However, the rotation of the distal axis tip does not follow exactly the rotation of the motor, since the catheter axis is not completely torsion-free a...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/5/001
更新日期:1998-05-01 00:00:00
abstract::Kinetic parameters are commonly estimated from dynamically acquired nuclear medicine data by first reconstructing a dynamic sequence of images and subsequently fitting the parameters to time-activity curves generated from regions of interest overlaid upon the image sequence. Biased estimates can result from images rec...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/4/024
更新日期:1998-04-01 00:00:00
abstract::Accurate scatter compensation in SPECT can be performed by modelling the scatter response function during the reconstruction process. This method is called reconstruction-based scatter compensation (RBSC). It has been shown that RBSC has a number of advantages over other methods of compensating for scatter, but using ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/4/014
更新日期:1998-04-01 00:00:00
abstract::This paper presents a Fourier rebinning algorithm for three-dimensional image reconstruction in PET that incorporates the concept of spectral transfer function. It suggests the need for discarding low-frequency components in the rebinning. It also includes the correction for rebinning efficiency which was evaluated by...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/4/004
更新日期:1998-04-01 00:00:00
abstract::The peak CT number (CT) and full width at half maximum (FWHM) were obtained from the image profiles of aluminium of thickness ranging from 0.1-9.5 mm. The scans were performed at different fields of view (FOVs) and with different reconstruction algorithms ('bone' and 'standard'). Above 3 mm, CT and FWHM provide measur...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/3/013
更新日期:1998-03-01 00:00:00
abstract::Spreadsheet templates which calculate cumulative exposures to other persons from patients to whom radioactive materials have been administered have been developed by the authors. Calculations can be based on any specified single-, bi- or tri-exponential whole-body clearance rate and a diurnal (or any other periodic) c...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/3/003
更新日期:1998-03-01 00:00:00
abstract::The prompt-gamma neutron activation facility at Brookhaven National Laboratory was upgraded to improve both the precision and accuracy of its in vivo determinations of total body nitrogen. The upgrade, guided by Monte Carlo simulations, involved elongating and modifying the source collimator and its shielding, reposit...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/2/009
更新日期:1998-02-01 00:00:00
abstract::We have developed an iterative method to correct axial and tangential patient motion occurring during tomographic acquisition. The method uses axial images reconstructed from the uncorrected projection images, which are then forward projected to form a basis for registering the original planar images and, in the proce...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/1/011
更新日期:1998-01-01 00:00:00
abstract::A three-dimensional spherical inclusion model that approximates a lesion bonded to a tissue matrix is proposed for biomedical elastography. Analytical formulae describing spatial strain and stress distributions generated in infinite media by uniform loading are given under a linear, homogeneous, isotropic elasticity a...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/43/1/001
更新日期:1998-01-01 00:00:00
abstract::To investigate the detection performance of our automated detection scheme for clustered microcalcifications on mammograms, we applied our computer-aided diagnosis (CAD) system to the database of the Mammographic Image Analysis Society (MIAS) in the UK. Forty-three mammograms from this database were used in this study...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/12/021
更新日期:1997-12-01 00:00:00
abstract::Densitometric quantification of coronary artery stenoses in angiographic images can be problematic for two reasons: (i) the x-rays are inadequately oriented with respect to the vessel segments of interest at image acquisition; (ii) non-linear effects due for instance to beam hardening, scattered radiation and veiling ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/12/011
更新日期:1997-12-01 00:00:00
abstract::High-resolution computations of induced fields are used to assess equivalent source levels for human exposure to uniform low-frequency electric and magnetic fields. These results pertain to 60 Hz foot-to-head electric excitation of the body in three positions with respect to a ground plane, and to magnetic excitation ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/12/001
更新日期:1997-12-01 00:00:00
abstract::The optical properties (absorption and scattering coefficients and the scattering anisotropy factor) were measured in vitro for cartilage, liver, lung, muscle, myocardium, skin, and tumour (colon adenocarcinoma CC 531) at 630, 632.8, 790, 850 and 1064 nm. Rabbits, rats, piglets, goats, and dogs were used to obtain the...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/11/017
更新日期:1997-11-01 00:00:00
abstract::In electron beam dosimetry using parallel-plate chambers solid phantoms are sometimes necessary. To obtain the dose to water from the ionization obtained in the solid phantom, fluence correction factors and perturbation factors have to be applied. In this study fluence factors in a perturbation free geometry have been...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/11/007
更新日期:1997-11-01 00:00:00
abstract::The bone mineral density (BMD), ultrasound velocity (UV) and attenuation were examined in sixteen matched sets of human patellae and calcanei. For the sixteen calcanei, BMD was strongly correlated with all ultrasound parameters. Calcaneal UV appeared to be inferior to attenuation in the ability to predict BMD. For the...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/10/008
更新日期:1997-10-01 00:00:00
abstract::Scattered radiation from within the treatment head can contribute significant dose to all parts of a radiotherapy treatment field. A multileaf collimator may be used to create an arbitrarily shaped field, and may also be used, under dynamic control, to modulate the beam intensity over the field. This method of intensi...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/9/006
更新日期:1997-09-01 00:00:00
abstract::Effects of different scatter compensation methods incorporated in fully 3D iterative reconstruction are investigated. The methods are: (i) the inclusion of an 'ideal scatter estimate' (ISE); (ii) like (i) but with a noiseless scatter estimate (ISE-NF); (iii) incorporation of scatter in the point spread function during...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/8/011
更新日期:1997-08-01 00:00:00
abstract::Techniques for reducing computation time in 3D photon dose calculations are addressed with specific emphasis given to the convolution/superposition approach. A single polyenergetic superposition model calculating absorbed dose per incident photon fluence (Gy cm2) was developed in terms of TERMA and a total energy depo...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/8/001
更新日期:1997-08-01 00:00:00
abstract::This paper introduces a spatial-diversity method for speckle suppression in optical coherence microscopy. The method is based on combining interference signals from an array of detectors placed in the back focal plane of the objective lens, such that elements receive light backscattered from the sample volume at diffe...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/7/015
更新日期:1997-07-01 00:00:00
abstract::The purpose of this investigation is to propose new compensator design strategies for protons and heavier particles which are based on pencil-beam (PB) dose calculations and which significantly reduce the dose to tissues downstream from the target, yet provide acceptable target coverage under conditions of patient mot...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/7/005
更新日期:1997-07-01 00:00:00
abstract::In interstitial heating one of the main requirements for achieving a certain elevated temperature in a tumour is that the effective power per applicator (Peff), i.e. the power which is actually deposited in the tissue, is sufficiently high. In this paper this requirement is discussed for the applicators of the 27 MHz ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/6/007
更新日期:1997-06-01 00:00:00
abstract::Biomedical fibre-optic sensors are attractive for the measurement of physical, chemical and biochemical parameters and for spectral measurements directly performed on the patient. An overview of fibre-optic sensors for in vivo monitoring is given, with particular attention paid to the advantages that these sensors are...
journal_title:Physics in medicine and biology
pub_type: 杂志文章,评审
doi:10.1088/0031-9155/42/5/015
更新日期:1997-05-01 00:00:00
abstract::We review the application of fluorescence spectroscopy and elastic-scattering spectroscopy, over the ultraviolet-to-visible wavelength range, to minimally invasive medical diagnostics. The promises and hopes, as well as the difficulties, of these developing techniques are discussed. ...
journal_title:Physics in medicine and biology
pub_type: 杂志文章,评审
doi:10.1088/0031-9155/42/5/005
更新日期:1997-05-01 00:00:00
abstract::Following the publication of ICRU Report 50, the concepts of GTV (gross tumour volume). CTV (clinical target volume) and PTV (planning target volume) are being used in radiotherapy planning with increasing frequency. In 3D planning, the GTV (or CTV) is normally outlined by the clinician in CT or MRI slices. The PTV is...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/4/011
更新日期:1997-04-01 00:00:00
abstract::A computerized system for monitoring dose-area product (DAP) has been developed for region of interest (ROI) fluoroscopy in which patient exposure is reduced using an x-ray attenuating filter with an aperture. The system includes an IBM compatible computer which is connected through an IEEE-488 interface to an electro...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/4/001
更新日期:1997-04-01 00:00:00
abstract::This paper presents finite-difference time-domain (FDTD) calculations of the whole-body averaged SAR in an anatomically realistic voxel model of the human body. This model, NORMAN, consists of approximately 9 million voxels, of 2 mm dimension in the adult phantom, segmented into 37 tissue types. SAR values are present...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/3/003
更新日期:1997-03-01 00:00:00
abstract::Recently, the initial 2D physical characterization of a small-diameter positron emission tomograph, designed specifically for scanning of small laboratory animals, was reported. The physical characteristics of the tomograph operating in 3D mode have now been measured and compared to those obtained in 2D mode. In 3D, t...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/2/010
更新日期:1997-02-01 00:00:00
abstract::The local noise property of a 3D PET reconstructed image is investigated for a uniform-activity sphere distributed in a constantly attenuating spherical object. The positional dependence of the statistical noise is approximately derived and calculated for some special cases. It is suggested that a larger diameter of t...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/1/015
更新日期:1997-01-01 00:00:00
abstract::A cost-effective method employing polysulphone, nalidixic acid, 8-methoxypsoralen and phenothiazine as UV dosimeters is presented for evaluating the UV spectrum. The exposure measured by each dosimeter is a function of the source spectrum and the spectral response of the material. Each material has a different spectra...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/42/1/005
更新日期:1997-01-01 00:00:00
abstract::A novel digital x-ray detector has been assembled. The imaging system is based on a phosphor-coated charge-coupled device (CCD) obtained by direct deposition of a gadolinium oxysulphide scintillator onto the detector surface. The modulation transfer function has been measured along the two directions of the digital co...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/41/12/016
更新日期:1996-12-01 00:00:00
abstract::Scatter correction is a prerequisite for quantitative SPECT, but potentially increases noise. Monte Carlo simulations (EGS4) and physical phantom measurements were used to compare accuracy and noise properties of two scatter correction techniques: the triple-energy window (TEW), and the transmission dependent convolut...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/41/11/017
更新日期:1996-11-01 00:00:00
abstract::Fixed-pattern noise in electronic portal images (EPIs) is normally eliminated by dividing raw image data by an open-field calibration image (OFCI). However, for successful elimination, there must be exact registration between the two image sets. Any movement within the imaging system, such as that which occurs with ga...
journal_title:Physics in medicine and biology
pub_type: 杂志文章
doi:10.1088/0031-9155/41/11/007
更新日期:1996-11-01 00:00:00